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Title   식도암의 방사선 치료 - 방사선 치료에 부가한 유도 화학요법 및 수술요법의 치료효과 비교 연구 - ( Esophageal Squamous Cell Carcinoma - Comparision of Radiotherapy alone to Chemo - radiotherapy combination with or without Surgery - )
Publicationinfo   1993 Jan; 025(01): 59-67.
Key_word   Esophageal squamous cell cancer, Radiotherapy, Chemotherapy
Full-Text  
Abstract   Survival of patients with localized cancer of the esophsgus treated with surgery and/or radiotherapy(RT) has been very poor. This has led to the incoporetion of effective cisplatin- based chemotherapy(CT) with RT or surgery(OP) sequentially with encouraging results. Since 1987, YUCC activated a nonrandomized treatment to evaluate 5000-6000 cGy radiation treatment following 2 ro 3 courses of 5-FU and Cisplatin with or without surgery. The current analysis was carried out on the 89 evaluable patients treated by 3 groups of treatment modali- ties. Thirty-six patients were entered into RT alone group, 39 patients were CT+RT group and 14 patients were CT+OP+ RT group. The survival for the entire patients at 12 and 24 months is 40.7 and 19.1%, respectively. The two-year survival for the RT alone, CT+RT group and CT+ OP+ RT group are 21.4%, 18.2% and 17.4%. We conclude that induction chemotherapy with or without operation is not superior to RT alone in patients with localized cancer of the esophagus. Further studies are needed to continue to improve on these results.
저 자   이형식(Hyung Sik Lee),허원주(Won Joo Hur),김귀언(Gwi Eon Kim),서창옥(Chang Ok Suh),노준규(Jun Kyu Loh),노재경(Jae Kyung Roh),김병수(Byung Soo Kim)